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Myles C Cabot Selected Research

(2R,3Z)- N- (1- hydroxyoctadec- 3- en- 2- yl)pivalamide

6/2012C6-ceramide and targeted inhibition of acid ceramidase induce synergistic decreases in breast cancer cell growth.
7/2011Inhibition of acid ceramidase by a 2-substituted aminoethanol amide synergistically sensitizes prostate cancer cells to N-(4-hydroxyphenyl) retinamide.

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Myles C Cabot Research Topics

Disease

41Neoplasms (Cancer)
01/2022 - 07/2002
15Breast Neoplasms (Breast Cancer)
01/2016 - 07/2002
10Acute Myeloid Leukemia (Acute Myelogenous Leukemia)
01/2022 - 09/2014
9Leukemia
01/2022 - 05/2004
4Colorectal Neoplasms (Colorectal Cancer)
01/2020 - 01/2003
3Pancreatic Neoplasms (Pancreatic Cancer)
03/2013 - 08/2011
3Ovarian Neoplasms (Ovarian Cancer)
07/2011 - 12/2003
3Colonic Neoplasms (Colon Cancer)
06/2010 - 05/2004
2Hematologic Neoplasms (Hematological Malignancy)
01/2021 - 11/2011
2Gaucher Disease (Gaucher's Disease)
01/2013 - 01/2010
2Neuroblastoma
08/2011 - 12/2010
2Prostatic Neoplasms (Prostate Cancer)
07/2011 - 05/2003
1Neoplasm Metastasis (Metastasis)
01/2016
1BCR-ABL Positive Chronic Myelogenous Leukemia (Chronic Myelogenous Leukemia)
10/2015
1Precursor Cell Lymphoblastic Leukemia-Lymphoma (Acute Lymphoblastic Leukemia)
10/2015
1Sphingolipidoses (Sphingolipidosis)
01/2013
1Triple Negative Breast Neoplasms
11/2012
1Adenocarcinoma
08/2011
1Uterine Cervical Neoplasms (Cancer of the Cervix)
12/2010
1Glioblastoma (Glioblastoma Multiforme)
12/2010
1Cardiovascular Diseases (Cardiovascular Disease)
01/2010
1Polyploidy
10/2007
1Leishmaniasis
12/2006
1Malaria
12/2006
1Melanoma (Melanoma, Malignant)
05/2004
1Squamous Cell Carcinoma (Epidermoid Carcinoma)
05/2004
1Ovarian Epithelial Carcinoma
12/2003

Drug/Important Bio-Agent (IBA)

35CeramidesIBA
01/2020 - 07/2002
15SphingolipidsIBA
01/2022 - 09/2008
12Pharmaceutical PreparationsIBA
01/2019 - 05/2004
10TamoxifenFDA LinkGeneric
01/2019 - 08/2010
10Member 1 Subfamily B ATP Binding Cassette TransporterIBA
01/2019 - 07/2002
10N-caproylsphingosineIBA
01/2017 - 08/2010
7ceramide glucosyltransferaseIBA
06/2013 - 05/2004
6Acid CeramidaseIBA
01/2019 - 07/2011
6EnzymesIBA
01/2018 - 12/2002
5FenretinideIBA
10/2015 - 12/2003
5Glucosylceramides (Glucocerebrosides)IBA
01/2013 - 05/2004
5Doxorubicin (Adriamycin)FDA LinkGeneric
06/2010 - 05/2004
4Proteins (Proteins, Gene)FDA Link
01/2020 - 05/2004
4Estrogen Receptor Modulators (Antiestrogen)IBA
01/2019 - 11/2012
3LipidsIBA
01/2018 - 10/2011
3sphingosine 1-phosphate (sphingosine-1-phosphate)IBA
12/2016 - 12/2013
3Estrogen ReceptorsIBA
09/2015 - 08/2011
3Hormones (Hormone)IBA
11/2012 - 05/2003
3Antineoplastic Agents (Antineoplastics)IBA
07/2011 - 09/2009
3OligonucleotidesIBA
06/2010 - 05/2004
2Adenosine Triphosphate (ATP)IBA
01/2021 - 01/2016
2Palmitic Acid (Hexadecanoic Acid)IBA
10/2015 - 05/2003
2valspodar (PSC 833)IBA
03/2013 - 07/2002
2(2R,3Z)- N- (1- hydroxyoctadec- 3- en- 2- yl)pivalamideIBA
06/2012 - 07/2011
2ATP-Binding Cassette Transporters (ABC Transporters)IBA
11/2011 - 12/2006
2Biological ProductsIBA
10/2011 - 05/2004
2retinamideIBA
07/2011 - 09/2008
1Electron Transport Complex I (NADH-CoQ Reductase)IBA
01/2022
1Oxaliplatin (Eloxatin)FDA LinkGeneric
01/2020
1Daunorubicin (Cerubidine)FDA LinkGeneric
01/2019
1Cytarabine (Cytosar-U)FDA LinkGeneric
01/2019
1Estrogen Receptor AntagonistsIBA
01/2017
1tariquidar (XR9576)IBA
01/2017
1Fulvestrant (Faslodex)FDA Link
01/2017
1IntegrinsIBA
01/2016
1RetinoidsIBA
10/2015
1SphingomyelinsIBA
10/2015
1BuffersIBA
09/2015
1triphenylethyleneIBA
09/2015
1N-desmethyltamoxifenIBA
07/2015
1APTIBA
12/2013
1Cytostatic AgentsIBA
03/2013
1Glucosylceramidase (Glucocerebrosidase)IBA
01/2013
1GemcitabineFDA Link
10/2011
1Messenger RNA (mRNA)IBA
08/2011
1Reactive Oxygen Species (Oxygen Radicals)IBA
08/2011
1Indicators and Reagents (Reagents)IBA
08/2011
1A-factor (Streptomyces)IBA
08/2011
1AmidesIBA
07/2011
1beta CateninIBA
06/2010
1safingol (sphinganine)IBA
09/2008
1dihydroceramideIBA
09/2008
13,5- dibromo- 4- (3,4- dimethoxyphenyl)- 1H- pyrrole- 2- carboxylic acid ethyl esterIBA
10/2007
1PyrrolesIBA
10/2007
1PoisonsIBA
10/2007
1Caspase 3 (Caspase-3)IBA
10/2007
1GlycolipidsIBA
05/2005
1Vinca AlkaloidsIBA
05/2004
1Antisense OligodeoxyribonucleotidesIBA
05/2004
1Vincristine (Oncovin)FDA LinkGeneric
05/2004
1Etoposide (VP 16)FDA LinkGeneric
05/2004
1Caspase 8 (Caspase-8)IBA
12/2003
1CaspasesIBA
12/2003
1Irinotecan (Camptosar)FDA LinkGeneric
01/2003
1CerebrosidesIBA
12/2002
1GangliosidesIBA
12/2002
1Serine C-PalmitoyltransferaseIBA
07/2002

Therapy/Procedure

14Drug Therapy (Chemotherapy)
01/2022 - 07/2002
13Therapeutics
01/2019 - 05/2004
1Lymph Node Excision (Lymph Node Dissection)
10/2002